报告讲座 > 正文

王鹏飞: DNA nanostructures - self-assembly, nanomaterial templating, and drug delivery
发布日期:2018-10-11  字号:   【打印

报告时间:2018年10月17日(星期三)14:30

报告地点:校学术会议中心第三会议室

  王鹏飞 研究员

工作单位上海交通大学医学院分子医学研究院

举办单位:化学与化工学院

报告人简介

王鹏飞,博士,上海交通大学医学院分子医学研究院研究员,博士生导师。2017年,入选中组部第十四批青年千人计划。

2007年、2009年获得天津大学材料科学工程学士、硕士学位,2014年获得美国普渡大学生物医学工程专业博士学位。2014-2018年,在美国埃默里大学与佐治亚理工学院生物医学工程学院从事博士后研究工作。

主要研究方向:核酸纳米结构自组装;疾病检测与治疗;癌症免疫治疗;智能生物纳米材料;合成生物学与超材料的制备。在Science、Nature、J. Am. Chem. Soc.、Angew. Chem. Int. Ed.、Small等国际高水平期刊发表论文19篇,综述3篇。先后荣获美国普渡大学Magoon 教学奖、美国心脏协会博士后奖学金。

报告简介

DNA acts as the genetic information carrier for most living organisms on the planet. Nonetheless, DNA is not merely the secret of life. Attributing to its programmability derived from the specific Watson-Crick base pairing, DNA has long been utilized as a smart molecular ligand, for instance, to direct the interactions between materials, or to probe biological systems. My research grounds on the foundation of structural DNA nanotechnology, where DNA is used as basic building blocks that are programmed to self-assemble into prescribed structures with unprecedented fidelity that nearly impossible to achieve by other techniques. In this talk, I will show you how we develop advanced self-assembly strategies to enrich the design toolbox of DNA self-assembly to allow people constructing structures with increased complexity. Furthermore, we have demonstrated exciting applications of DNA nanostructures by organizing non-biological (e.g. gold nanoparticles) and biological (e.g. siRNAs) functional materials onto DNA structures for applications in fabricating nanodevices and drug delivery.

(李育林/文)  
编辑:徐小红
0